Upstream Bioprocess Development Scientist
Elanco
Summary
As an Upstream Bioprocess Development Scientist, you will be part of the Bioprocess Development team to deliver robust upstream platforms for Elanco's Biotherapeutic portfolio. In this role, you will be responsible for advancing upstream process development from flask models through bioreactor scales while partnering closely with Downstream, Formulations, and Analytical scientists to drive a culture of innovation and scientific excellence.
Job description
Your Responsibilities
- Conceive, plan, schedule, and execute laboratory experiments across multiple models and scales (ranging from shake flasks to bioreactors) to develop highly robust, consistent processes for the Large Molecule portfolio.
- Apply Quality by Design (QbD) principles and Design of Experiments (DOE) methodologies to evaluate multi-factor interactions, optimize product quality and yield, and support regulatory/quality initiatives.
- Maintain laboratory infrastructure and an organized, clean, and safe working environment; schedule and perform instrument/equipment maintenance, evaluate new laboratory equipment, and ensure strict adherence to biohazard and hazardous chemical safety protocols.
- Ensure complete technical data integrity, analyze and interpret complex datasets to inform subsequent experimental design, and communicate findings to peers, cross-functional teams, and senior leadership.
- Author technical reports, SOPs/working procedures, external publications, and sections for regulatory registration submissions, while leading process troubleshooting, knowledge transfer, and providing on-site person-in-plant technical coverage at manufacturing facilities.
What You Need to Succeed (minimum qualifications)
- Education: Bachelor's Degree in Biology, Molecular Biology, Microbiology, or related scientific discipline (or equivalent level of experience).
- Experience: Minimum of five years of hands-on experience working with mammalian cell lines or similar.
- Top Skills: Strong laboratory skills in cell culture / bioreactor operation and foundational knowledge of bioprocess / Design of Experiments (DOE) principles.
What will give you a competitive edge (preferred qualifications)
- Experience with upstream cell culture scale-up and technology transfer to pilot or manufacturing facilities.
- Experience working in regulated (e.g., cGMP, FDA, USDA, EMA) and BSL-1 / BSL-2 laboratory environments.
- Broad exposure to or understanding of adjacent technical platforms (e.g., fermentation, analytical method development, purification, or formulation development).
- Demonstrated strategic problem-solving capabilities, adaptability, and strong collaborative communication skills.
- Prior experience within the Animal Health or Biopharmaceutical industry.
Requirements
- Bachelor's Degree in Biology, Molecular Biology, Microbiology, or related scientific discipline (or equivalent level of experience).
- Minimum of five years of hands-on experience working with mammalian cell lines or similar.
- Strong laboratory skills in cell culture / bioreactor operation.
- Foundational knowledge of bioprocess / Design of Experiments (DOE) principles.
Benefits
- Relocation packages
- Two weeklong shutdowns
- 8-week parental leave
- 9 Employee Resource Groups
- Annual bonus
- Flexible work arrangements
- Up to 6% 401K matching
Company overview
Elanco Animal Health Incorporated is a global leader in the animal health pharmaceutical industry, dedicated to improving the health and well-being of both pets and farm animals worldwide. Founded in 1954 as a division of Eli Lilly and Company, Elanco became an independent public company in 2018 and has since grown to become the world's second-largest independent animal health company. With approximately 9,000 employees globally, the company operates with a clear purpose: 'making life better for animals, makes life better.' Elanco develops innovative medicines, vaccines, and health solutions that empower veterinarians, farmers, and pet owners to advance animal care. The company maintains a balanced portfolio between pet health and farm animal products, offering over 200 brands that address critical health challenges ranging from companion animal diseases to livestock productivity. Headquartered in Indianapolis, Indiana, Elanco is publicly traded on the New York Stock Exchange (NYSE: ELAN) and continues to drive innovation in animal health through strategic acquisitions and dedicated research and development efforts.