
US Forecasting Leader – R&I
AstraZeneca
Summary
This role leads US forecasting for a dynamic portfolio for respiratory, turning integrated insights into clear direction for launch and in-line brands. You will partner closely with Commercial, Competitive Intelligence, Finance, Medical, Market Access, Pricing and other senior stakeholders to align assumptions, pressure-test scenarios, and translate complex analytics into decisive actions that move the business forward.
Job description
Accountabilities
- US Forecast Ownership: Lead the development and delivery of robust US forecasts across annual planning, long-range planning, forecast updates and business reviews, ensuring clarity of drivers and confidence ranges.
- Market Subject-Matter Leadership: Serve as the forecasting authority for prioritized markets and disease areas, bringing evidence-based viewpoints that shape commercial strategy.
- Patient-based Modeling: Build patient-based models in Excel using credible assumptions synthesized from primary and secondary sources and benchmarked to relevant analogs; quantify risks, opportunities and uncertainty.
- Scenario Planning and Storytelling: Develop scenarios that reflect business ambition and constraints; distill complex analyses into compelling narratives for senior commercial, medical and finance audiences.
- Performance Tracking and Action: Monitor actuals versus forecast, diagnose variances, and recommend updates or targeted interventions to improve performance.
- Customer Insight Advocacy: Champion the use of local customer insights in strategic and operational decisions, ensuring forecasts reflect real market dynamics.
- Cross-functional Alignment: Facilitate forecast reviews and assumption-alignment sessions; document decisions, dissenting views, risks and follow-ups to maintain momentum and governance.
- Capability Transformation: Identify, develop and embed new forecasting and analytics capabilities; drive adoption and integration across teams to elevate decision quality.
- AI-enabled Forecasting and Automation: Validate and scale generative AI and advanced automation to improve forecasting efficiency and scenario agility while maintaining rigorous governance and compliance.
- Continuous Improvement Culture: Promote learning, testing and rapid deployment of new methods; mentor teams to raise standards and speed without sacrificing quality.
- External Scanning: Track emerging analytics and forecasting practices within and beyond pharma to bring differentiated advantages to the organization.
Essential Skills/Experience
- 8+ years of pharmaceutical industry experience including revenue forecasting utilizing epidemiology-based methodologies, claims, EHR/EMR, and other patient-level datasets, sales data analysis and qualitative/quantitative primary market research.
- Proficiency in accessing, analyzing, and interpreting large longitudinal patient-level datasets, including open and closed medical claims, EHR/EMR data, IQVIA prescription and sales data, and other syndicated data sources.
- MS Office with advanced proficiency in Microsoft Excel and PowerPoint.
- Bachelor's degree from an accredited college or university.
Desirable Skills/Experience
- Advanced modeling skills using Visual Basic, Power BI, SQL + R or Python are preferred.
- Excellent communication and influencing skills, combined with strong leadership and interpersonal skills and demonstrated ability to work with senior business leaders and cross-functional business partners.
- Strategic and critical thinking with the ability to engage, build and maintain credibility with Commercial Leadership teams.
- Ability to manage a diverse range of simultaneous projects, timelines, and priorities with both internal stakeholders and external vendors.
- An advanced degree is preferred (Master's, MBA, or PhD).
Requirements
- 8+ years of pharmaceutical industry experience
- Revenue forecasting utilizing epidemiology-based methodologies
- Experience with claims, EHR/EMR, and other patient-level datasets
- Sales data analysis and qualitative/quantitative primary market research
- Proficiency analyzing large longitudinal patient-level datasets
- Experience with IQVIA prescription and sales data and syndicated data sources
- Advanced proficiency in Microsoft Excel and PowerPoint
- Bachelor's degree from an accredited college or university
- Advanced modeling skills using Visual Basic, Power BI, SQL, R or Python (preferred)
- Excellent communication and influencing skills
- Strong leadership and interpersonal skills
- Strategic and critical thinking
- Ability to manage multiple projects, timelines, and priorities
- Advanced degree such as Master's, MBA, or PhD (preferred)
Benefits
- Retirement programs
- Paid time off
- Health insurance
- Dental insurance
- Vision coverage
- Short-term incentive bonuses
- Equity-based awards
Company overview
AstraZeneca is a global, science-led, patient-focused pharmaceutical company dedicated to accelerating the delivery of life-changing medicines that create enduring value for patients, society, and shareholders. With a workforce of over 94,300 employees worldwide, the company operates across three core therapy areas: Oncology, BioPharmaceuticals (including Cardiovascular, Renal & Metabolism, Respiratory & Immunology), and Rare Disease. Headquartered in Cambridge, UK, AstraZeneca maintains strategic R&D centers in Cambridge, Gaithersburg (US), Boston (US), Gothenburg (Sweden), Shanghai, and Beijing. The company generated $54.1 billion in total revenue in 2024 and invested $13.6 billion in scientific research and development. AstraZeneca's bold aspiration is to be pioneers in science, lead in disease areas, and transform patient outcomes, with a goal to launch 20 new medicines and achieve $80 billion in total revenue by 2030. The company is recognized for its commitment to sustainability, health equity, and creating an inclusive work environment where diverse perspectives drive innovation.