Vice President, Clinical Pharmacology & Pharmacometrics

The Impact You'll Make

As Vice President, Clinical Pharmacology & Pharmacometrics, you will set the enterprise strategy for clinical pharmacology, pharmacometrics, and model-informed drug development across Recursion's advancing clinical portfolio. You will be accountable for translating nonclinical, translational, biomarker, clinical, and quantitative data into development decisions that help us select the right dose, regimen, population, and study design for each program.

Your team will bring together expertise across Clinical Pharmacology, Pharmacometrics, Translational Modeling, and preclinical PK/PK-PD, with close partnership across Toxicology, DMPK, Nonclinical Safety, Clinical Biomarkers, Clinical Development, Regulatory, Biostatistics, CMC, Data Science, and Portfolio Strategy. This is a highly strategic leadership role for a clinical pharmacology leader who can operate from first-in-human planning through registrational development, regulatory submission, and label strategy.

In this role, you will:

• Set the enterprise strategy for Clinical Pharmacology, Pharmacometrics, Translational Modeling, and preclinical-to-clinical quantitative integration across Recursion's clinical and post-candidate nomination portfolio
• Own dose strategy from first-in-human planning through registrational development, including dose escalation, dose optimization, exposure-response, safety, efficacy, and label-supporting dose justification
• Lead quantitative development approaches, including population PK, PK/PD, exposure-response, PBPK, QSP, disease progression modeling, and clinical trial simulations
• Design and oversee clinical pharmacology studies, including food effect, DDI, organ impairment, QT/cardiac safety, bioavailability/bioequivalence, mass balance/ADME, and special population studies
• Partner cross-functionally with Clinical Development, Development Sciences, DMPK, Toxicology, Translational Modeling, Biomarkers, Regulatory, Biostatistics, CMC, and Data Science to inform development strategy and decision-making
• Represent Recursion as the clinical pharmacology expert in regulatory interactions and ensure high-quality clinical pharmacology contributions to INDs/CTAs, briefing books, NDAs/BLAs/MAAs, regulatory responses, and labeling
• Represent Clinical Pharmacology and Translational Modeling in cross-functional program teams, governance forums, regulatory interactions, and alliance settings with Recursion's external pharma partners
• Build, mentor, and scale a high-performing Clinical Pharmacology and Pharmacometrics function, including internal talent, consultants, CROs, and external modeling partners
• Advance the responsible use of AI, automation, and advanced analytics to improve evidence integration, modeling workflows, and clinical development decisions

The Team You'll Join

You will join Recursion's Clinical Development organization, reporting to the Chief Medical Officer. The Clinical Development team is an empowered, execution-minded group responsible for translating Recursion's innovative science into medicines for patients. You will work closely with leaders across Development, Regulatory, Development Sciences, Clinical Operations, Data Science, Biology, Chemistry, Portfolio Strategy, Communications, Legal/Compliance, and future commercialization functions.

The Experience You'll Need

• Advanced degree in clinical pharmacology, pharmacometrics, pharmaceutical sciences, quantitative pharmacology, biomedical engineering, medicine, pharmacy, or a related field; PhD, PharmD, or MD preferred
• 15+ years of biotech or pharmaceutical industry experience, including significant leadership experience in Clinical Pharmacology, Pharmacometrics, Quantitative Pharmacology, or model-informed drug development
• Proven success leading clinical pharmacology strategy across multiple programs, ideally from first-in-human studies through registrational development, submission, and labeling
• Deep expertise in PK, PK/PD, exposure-response, exposure-safety, population PK, PBPK, QSP, dose optimization, dose justification, and model-based clinical trial design
• Experience designing, interpreting, and defending clinical pharmacology studies and analyses in support of global development and regulatory submissions
• Strong understanding of FDA, EMA, MHRA, PMDA, and ICH expectations for clinical pharmacology, pharmacometrics, dose selection, MIDD, and regulatory documentation
• Demonstrated ability to build and lead high-performing teams, influence senior stakeholders, manage external partners, and communicate complex quantitative concepts clearly to executives, program teams, partners, and regulators
• Experience in oncology, rare disease, and/or small molecule development strongly preferred; experience applying AI, advanced analytics, or automation in clinical pharmacology is a plus