Vice President - Oncology Clinical Development, Disease Area Head- Hematology

Key Responsibilities

• Accountable for end-to-end clinical development of oncology assets from first-in-human (FTIH) studies through proof-of-concept studies, registrational trials, regulatory approval, and initial market launch.
• Shape and drive the scientific and clinical development strategy for assigned disease areas and assets, aligned with Oncology Tumor Team strategy and broader Oncology portfolio priorities.
• Ensure deep integration of clinical, and disease-area expertise into preclinical and translational research activities to optimize asset positioning, biomarker strategy, and development strategy and decisions.
• Evaluate, champion, and enable the use of novel approaches (e.g., AI/ML, innovative trial designs, external and real-world data sources) where they add clear scientific, operational, or decision-making value to clinical development.
• Provide program-level oversight and leadership, while ensuring connectedness both cross functionally and across assets, maintaining visibility to progress, risks, dependencies, and trade-offs across the Oncology portfolio.
• Serve as the senior clinical representative at key governance forums for assigned programs, ensuring strong clinical leadership, continuity, and high-quality decision-making.
• Represent the Oncology Clinical Development organization internally and externally, including presenting at high-impact forums such as congress all-hands, senior leadership reviews, and advisory boards.
• Lead scientific advisory boards and other external engagements to inform asset strategy, competitive positioning, and portfolio decisions, incorporating emerging science and external expert insight.
• Co-lead asset development with matrix leadership partners, driving alignment across research, development, and commercialization planning, and ensuring cohesive execution against shared objectives.
• Lead with an enterprise mindset: Act as a senior connector across functions, partnering closely with Oncology Research, Translational Research, Translational Medicine, Medical Affairs, Global Product Strategy, and Confidential Competitive Intelligence to drive integrated development and lifecycle planning.
• Build and sustain strong internal and external partnerships to accelerate decision-making, resolve complexity, and optimize development outcomes in a matrixed environment.
• Line-manage and mentor Clinical Development Leads, Clinical Science Program Leads, Medical Directors, and Clinical Scientists, with clear accountability for performance, development, engagement, and succession planning.
• Provide clarity on roles, expectations, and career paths within Oncology Clinical Development, contributing to role definitions, capability frameworks, and targeted training strategies.
• Foster a culture of empowerment, enterprise-level drug development, scientific excellence, inclusion, and collaboration, aligned with OneOncology values, while modeling strong, visible leadership.
• Actively remove organizational barriers and enable teams to operate effectively and autonomously within a complex, global matrix environment.
• Contribute to the establishment and continuous evolution of clinical development standards, processes, and best practices across Oncology, ensuring consistency, quality, and regulatory readiness.
• Ensure timely access to relevant external scientific and competitive intelligence (e.g., congress data, emerging science, competitor activity) to inform clinical development decisions and portfolio strategy.

Key Characteristics

• Expertise in Hematology/Oncology Therapeutic Knowledge: Comprehensive understanding of hematologic cancers, including disease biology, treatment paradigms, and unmet patient needs and opportunities.
• Clinical Development Excellence: Expertise in designing and executing clinical trials, including early-phase first-in-human and proof-of-concept studies and late-phase pivotal trials.
• Regulatory Acumen: Familiarity with regulatory requirements and processes across major health authorities (FDA, EMA, etc.).
• Scientific Credibility: Established track record of publications, presentations, or contributions to the oncology field.
• Strategic Planning: Develop and execute a comprehensive clinical development strategy for hematologic cancer programs.
• Cross-functional Leadership: Lead multidisciplinary teams, including clinical scientists, medical directors, regulatory affairs, and biostatistics professionals.
• Portfolio Oversight: Provide oversight for multiple drug candidates and clinical trials, ensuring alignment with corporate goals and therapeutic priorities.
• Innovation: Champion novel approaches to drug development, including biomarker-driven strategies, precision medicine, and immuno-oncology therapies.
• Budget and Resource Management: Manage financial and personnel resources efficiently to meet clinical development milestones.
• Risk Management: Identify, mitigate, and manage risks in clinical programs (e.g., safety issues, trial delays, data challenges).
• Data-Driven Decision Making: Leverage clinical trial data and real-world evidence to inform program direction and strategy.
• Internal Collaboration: Foster strong relationships with internal stakeholders, including R&D leadership, commercial teams, and research units.
• External Partnerships: Build and maintain partnerships with external collaborators, such as academic institutions, contract research organizations (CROs), and patient advocacy groups.
• Communication Skills: Effectively communicate complex scientific and strategic concepts to diverse audiences, including executive leadership and external stakeholders.
• Unmet Needs: Prioritize addressing critical unmet needs for patients with hematologic cancers through innovative treatments.
• Patient Engagement: Support initiatives to engage patients and integrate their perspectives into clinical development programs.
• Equity in Access: Ensure clinical trials are designed to be accessible and inclusive for diverse patient populations.
• Visionary Leadership: Inspire teams with a clear vision and passion for advancing oncology therapeutics.
• Mentorship: Provide guidance and mentorship to team members, fostering professional growth and development.
• Adaptability: Demonstrate flexibility in responding to evolving scientific, regulatory, and market dynamics.
• Results-Oriented: Focus on achieving measurable outcomes that drive progress in GSK's oncology portfolio.
• Integrity: Uphold GSK’s core values, ensuring ethical conduct in all aspects of clinical development.
• Innovation: Champion GSK’s commitment to innovation in oncology research and development.
• Collaboration: Foster teamwork and inclusivity consistent with GSK’s culture.